Can Some Marine-Derived Fungal Metabolites Become Actual Anticancer Agents?
نویسندگان
چکیده
منابع مشابه
Can Some Marine-Derived Fungal Metabolites Become Actual Anticancer Agents?
Marine fungi are known to produce structurally unique secondary metabolites, and more than 1000 marine fungal-derived metabolites have already been reported. Despite the absence of marine fungal-derived metabolites in the current clinical pipeline, dozens of them have been classified as potential chemotherapy candidates because of their anticancer activity. Over the last decade, several compreh...
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In order to control microbial resistance against commonly used antibiotics, it is indispensable to develop novel and efficient antimicrobial agents. For this purpose, metallic nanoparticles (mainly inorganic) with their antimicrobial activites represent an effective solution for this global problem. However, synthesis of nanoparticles involves the use of expensive, poisonous and dangerous chemi...
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The chemical investigation of marine mollusks has led to the isolation of a wide variety of bioactive metabolites, which evolved in marine organisms as favorable adaptations to survive in different environments. Most of them are derived from food sources, but they can be also biosynthesized de novo by the mollusks themselves, or produced by symbionts. Consequently, the isolated compounds cannot...
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Alkaloids are naturally occurring nitrogen containing biologically active heterocyclic compounds. Over the last few years, a large number of biologically important alkaloids with antiviral, antibacterial, anti-inflammatory, antimalarial, antioxidant and anticancer activities have been isolated from marine source. Present article summarizes the isolation and anticancer activity evaluation of nat...
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The selective inhibition of PTP1B has been widely recognized as a potential drug target for the treatment of type 2 diabetes and obesity. In the course of screening for PTP1B inhibitory fungal metabolites, the organic extracts of several fungal species isolated from marine environments were found to exhibit significant inhibitory effects, and the bioassay-guided investigation of these extracts ...
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ژورنال
عنوان ژورنال: Marine Drugs
سال: 2015
ISSN: 1660-3397
DOI: 10.3390/md13063950